You had one ‘perfect’ copy of DNA in your chromosomes when you were a single cell fertilized ege. Since then, each copy has made successive generations progressively worse
CRISPR-Cas is not like a human finding cutting and splicing an old fashioned movie reel…it depends on bacterial-derived micro-machines with an inherent error rate.
Yesterday, we lost a great soul when Stein Erickson, Norwegian Olympian and Johnny Appleseed of Skiing in America passed away of “natural causes” at age 88.