I have been taking TA-65 for 5 years with no tendon problems. In addition to consulting with traditional medical doctors, I also work with intuitive practitioners one of which reported that the TA-65 was making the organs in my torso younger but not as much improvement on my tendons due to lower blood circulation in those parts of the body. As someone who lifts weights regularly for exercise, I also take a number of nutritional supplements with the hope that they will compliment the effects of TA-65. Quantum mechanics is relevant here as the human body shifts between energy and matter similar to sub-atomic particles. When we sleep, the body moves into the energy state, and during the work day moves into the matter state. In addition, the human baby (sleeps a lot) spends more time in the energy state while the elderly (difficulty sleeping) spends more time in the matter state. More time in the matter state corresponds with crystallization of the body and hence less flexibility, i.e., as we age the body crystalizes and tends toward less flexibility while the young spring back from physical impacts due to their greater flexibility (non-crystal state). For those who wish to understand this better, I recommend the book “Wisdom of the Gemstone Guardians” by Michael Katz, however as a warning, this book is of a mystical and not scientific nature. If you are looking for “evidence based” information, this book is not within that category.