This article describes exactly what I’ve been saying for the last 6 years. My book, “Telomere Timebombs: defusing the terror of aging” outlines this exact and obvious conclusion: maintaining stem cell telomere integrity will allow for longer and healthier lives.
Will another 6 years go by before we can get everyone to recognize the obviousness of my theory of aging?
Actually, the paper described perfectly validates my theory about clonality and it’s importance in median telomere measurements. This patient’s entire blood lines came from the last two remaining stem cells she had. As I mentioned in my blog posting, the length of telomeres is a function of which clonal ancestors survive. See this blog for more info:
So what is going on here? Well without sufficient telomerase activity, you run out immune cell progenitor stem cells. So as I discuss in this video, AIDS is aging and aging is a form of acquired immune deficiency.
Luckly, this paper from UCLA proved that treatment with an Astragalus derivative, cycloastrogenol, can rehabilitate HIV infected T-Cells so maybe this is would also apply to the hematopoetic stem cells that are described to be at the heart of aging and surviving in the case of folks over 110?